For Healthcare Professionals Login to the Nplate® NEXUS Program
Support & Follow Up
What Do I Do for the Nplate® NEXUS Program During Nplate® Treatment?
  • Order Nplate® for your patients through your primary wholesaler or call 1-877-NPLATE1
    (1-877-675-2831). Healthcare providers should only order enough Nplate® to meet the immediate needs of individual enrolled patients.
  • Provide each patient with the Medication Guide prior to each Nplate® injection.
  • Promptly report any adverse events associated with the use of Nplate® to the Nplate® NEXUS Program at 1-877-675-2831 or FDA’s MedWatch Program at 1-800-FDA-1088.
  • Twice a year, verify your patient roster, then complete and submit an Nplate® NEXUS Safety Questionnaire for each patient by fax (1-877-NPLATE0 [1-877-675-2830]) or phone (1-877-NPLATE1 [1-877-675-2831]). You will verify that each patient should continue on Nplate®.
  • For any report of an adverse event, Amgen will follow up for more information.
    You can provide more detailed information by submitting the MedWatch form by fax
    (1-877-NPLATE0 [1-877-675-2830]) or by giving the information over the phone
    (1-877-NPLATE1 [1-877-675-2831]).
Nplate® NEXUS Safety Questionnaire
The FDA Safety Information and Adverse Event Reporting Program - MedWatch Form
What Do I Do If a Patient Discontinues Nplate® Treatment?
  • Complete and submit the Nplate® NEXUS Program Discontinuation/Post-Discontinuation Follow-up Form. The form can be submitted by fax (1-877-NPLATE0 [1-877-675-2830]) or phone (1-877-NPLATE1 [1-877-675-2831]).
  • Call 1-877-NPLATE1 (1-877-675-2831) to inquire about product returns.
Nplate® NEXUS Program Discontinuation/Post-Discontinuation Follow-up Form
What ITP Reimbursement Support Is Available?
The Nplate® NEXUS Program will provide optional ITP reimbursement assistance to patients and healthcare providers.

ITP reimbursement services include:
- Verifying insurance coverage
- Assisting with alternative funding options
- Assistance with prior authorizations, claims, denials, and appeals
Go to the Nplate® Reimbursement Connection page